Tang H R, Hancock R A, Covington A D
Department of Chemistry, Royal Holloway and Bedford New College, Egham, Surrey, United Kingdom.
Basic Life Sci. 1992;59:221-43. doi: 10.1007/978-1-4615-3476-1_13.
Current research has focused on the composition of commercially used chestnut tannin extracts so as to provide a quantitative basis for studies of reactions, structure-property relationships, and applications of chestnut tannin extract. Two chestnut tannins, vescalagin and castalagin, have been isolated using chromatography on Sephadex LH-20 and cellulose. The structures of these compounds have been established by means of nuclear magnetic resonance and fast atom bombardment mass spectroscopy. Some other components have been found and analyzed by chromatography and spectroscopy, but their structures have not as yet been completely defined. These structural features, together with quantitative results for each component, provide a better understanding of the mode of action of complex commercial chestnut tannin extracts.
目前的研究集中在商业用栗木单宁提取物的成分上，以便为栗木单宁提取物的反应、结构-性质关系及应用研究提供定量依据。使用葡聚糖凝胶LH-20和纤维素柱色谱法分离出了两种栗木单宁，即vescalagin和castalagin。这些化合物的结构已通过核磁共振和快原子轰击质谱法确定。通过色谱法和光谱法还发现并分析了一些其他成分，但其结构尚未完全确定。这些结构特征以及每种成分的定量结果，有助于更好地理解复杂的商业栗木单宁提取物的作用方式。
