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变形链球菌6715株的胞外葡聚糖水解酶

Extracellular dextran hydrolase from Streptococcus mutans strain 6715.

作者信息

Ellis D W, Miller C H

出版信息

J Dent Res. 1977 Jan;56(1):57-69. doi: 10.1177/00220345770560011301.

DOI:10.1177/00220345770560011301
PMID:14177
Abstract

Streptococcus mutans strain 6715 was shown to produce an extracellular dextramase with endohydrolytic alpha-(1 leads to 6)-glucan-6-glucanohydrolase activity. The enzyme degraded soluble polymers produced by some oral streptococci but did not disperse the streptococcal plaques tested. Enzyme levels in the culture supernatant were elevated in sucrose and sucrose plus glucose cultures but remained at basal levels in glucose and dextran plus glucose cultures.

摘要

变形链球菌6715菌株被证明能产生一种具有内切水解α-(1→6)-葡聚糖-6-葡聚糖水解酶活性的细胞外右旋糖酶。该酶能降解一些口腔链球菌产生的可溶性聚合物,但不能分散所测试的链球菌菌斑。在蔗糖以及蔗糖加葡萄糖的培养物中,培养上清液中的酶水平升高,但在葡萄糖以及葡聚糖加葡萄糖的培养物中,酶水平保持在基础水平。

相似文献

1
Extracellular dextran hydrolase from Streptococcus mutans strain 6715.变形链球菌6715株的胞外葡聚糖水解酶
J Dent Res. 1977 Jan;56(1):57-69. doi: 10.1177/00220345770560011301.
2
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Dextranase activity of streptococcal isolates from human dental plaques.从人类牙菌斑中分离出的链球菌的右旋糖酐酶活性。
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Streptoccus mutans dextransucrase: purification, properties, and requirement for primer dextran.变形链球菌葡糖基转移酶:纯化、特性及对引物葡聚糖的需求
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Measurement and synthesis of insoluble and soluble dextran by Streptococcus mutans.
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引用本文的文献

1
Microbial dextran-hydrolyzing enzymes: fundamentals and applications.微生物葡聚糖水解酶:基础与应用
Microbiol Mol Biol Rev. 2005 Jun;69(2):306-25. doi: 10.1128/MMBR.69.2.306-325.2005.
2
Purification and characterization of Streptococcus sobrinus dextranase produced in recombinant Escherichia coli and sequence analysis of the dextranase gene.重组大肠杆菌产生的嗜sobrinus链球菌葡聚糖酶的纯化与表征及葡聚糖酶基因的序列分析
J Bacteriol. 1994 Jul;176(13):3839-50. doi: 10.1128/jb.176.13.3839-3850.1994.
3
Overproduction of a dextranase inhibitor by Streptococcus sobrinus mutants.
远缘链球菌突变体过量产生一种葡聚糖酶抑制剂。
J Bacteriol. 1994 Dec;176(23):7206-12. doi: 10.1128/jb.176.23.7206-7212.1994.
4
Purification, characterization, and specificity of dextranase inhibitor (Dei) expressed from Streptococcus sobrinus UAB108 gene cloned in Escherichia coli.从克隆于大肠杆菌的远缘链球菌UAB108基因表达的葡聚糖酶抑制剂(Dei)的纯化、特性鉴定及特异性研究
J Bacteriol. 1995 Apr;177(7):1703-11. doi: 10.1128/jb.177.7.1703-1711.1995.
5
Biology, immunology, and cariogenicity of Streptococcus mutans.变形链球菌的生物学、免疫学及致龋性
Microbiol Rev. 1980 Jun;44(2):331-84. doi: 10.1128/mr.44.2.331-384.1980.
6
Purification and partial characterization of the multicomponent dextranase complex of Streptococcus sobrinus and cloning of the dextranase gene.变形链球菌多组分葡聚糖酶复合物的纯化、部分特性鉴定及葡聚糖酶基因的克隆
Infect Immun. 1987 Mar;55(3):792-802. doi: 10.1128/iai.55.3.792-802.1987.
7
Molecular cloning of the extracellular endodextranase of Streptococcus salivarius.唾液链球菌胞外内切葡聚糖酶的分子克隆
J Bacteriol. 1991 Dec;173(23):7423-8. doi: 10.1128/jb.173.23.7423-7428.1991.
8
More sensitive test agar for detection of dextranase-producing oral streptococci and identification of two glucan synthesis-defective dextranase mutants of Streptococcus mutans 6715.用于检测产葡聚糖酶口腔链球菌及鉴定变形链球菌6715的两个葡聚糖合成缺陷型葡聚糖酶突变体的更灵敏测试琼脂。
J Clin Microbiol. 1979 Dec;10(6):919-22. doi: 10.1128/jcm.10.6.919-922.1979.