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GENETIC REGULATORY MECHANISMS AT THE POPULATION LEVEL IN MAN.

作者信息

PARSONS P A

出版信息

Science. 1964 Nov 13;146(3646):924-5. doi: 10.1126/science.146.3646.924.

DOI:10.1126/science.146.3646.924
PMID:14199713
Abstract

The distribution of the Rhesus and ABO blood groups, thalassemia, and glucose-6-phosphate dehydrogenase deficiency in Europe and in Jewish populations argues for a regulatory mechanism at the population level which adjusts gene frequencies so that the overall genetic load is not excessive, since gene frequencies giving a high genetic load at one locus are often associated with those giving low genetic loads at other loci.

摘要

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