dell'Agnola C A, Carmassi L, Tadini B, Ghisoni L, Carmignani L
Department of Pediatric Surgery, University of Milan, Italy.
Eur J Pediatr Surg. 1992 Oct;2(5):274-6. doi: 10.1055/s-2008-1063457.
Between 1989 and 1990, 31 new unilateral PUJO, prenatally diagnosed (16th-37th week of gestational age), underwent pyeloplasty between 19 and 105 days of age. The correlation between severity (V) (volume of hydronephrotic kidney) and duration (dT) of congenital hydronephrosis from its first detection in utero to surgery and histological findings were prospectively evaluated in this series. A dT longer than 70 days and a V larger than 50 ml., were considered as predictable for hypotrophy with fibrosis of the upper urinary tract smooth musculature. In conclusion, time seems to play an important role in the increase of the volume of the obstructed urinary tract to the extent of a large-scale hydronephrosis.
1989年至1990年间，31例产前诊断（孕龄16至37周）的新发单侧肾盂输尿管连接部梗阻（PUJO）患儿在19至105日龄时接受了肾盂成形术。本系列前瞻性评估了先天性肾积水严重程度（V）（肾积水肾脏体积）、从子宫内首次发现至手术的先天性肾积水持续时间（dT）与组织学结果之间的相关性。dT超过70天且V大于50毫升被认为可预测上尿路平滑肌组织萎缩伴纤维化。总之，时间似乎在梗阻性尿路体积增加至大规模肾积水程度的过程中起重要作用。
