Förström L, Hannuksela M, Idänpään-Heikkilä J, Salo O P
Dermatologica. 1977;154(6):367-9. doi: 10.1159/000251096.
Procaine chloride, which was a common cause of allergic reactions in earlier years, has lost importance as a contact allergen because its use for local anesthesia has ceased. Recently, we have seen hypersensitivity reactions in three patients after the use of Gerovital, which is known to contain procaine chloride. A word of warning is warranted against indiscriminate use of Gerovital, particularly of its topical preparations.
早年曾是过敏反应常见病因的氯化普鲁卡因,由于其已不再用于局部麻醉,作为接触性变应原已不再重要。最近,我们发现3例患者在使用已知含有氯化普鲁卡因的Gerovital后出现了超敏反应。有必要对不加区分地使用Gerovital,尤其是其外用制剂发出警告。