Liñana Santafé J J, Calvo Catalá F J, Hortelano Martínez E, González-Cruz I, Martínez San Juan V
Unidad de Reumatología, Hospital General Universitario, Valencia.
An Med Interna. 1992 Oct;9(10):498-500.
Two clinical cases of patients with rheumatoid arthritis (RA) and poor response to conventional treatment are described. Patients received immunosuppressor treatment with azathioprine (AZA) and developed hepatic hemangiomas without detectable hepatic pathology previous to the treatment with AZA. The hepatic iatrogenesis of AZA is discussed, as well as the etiopathogenic hypothesis regarding hepatic hemangioma.
本文描述了两例类风湿关节炎(RA)患者对传统治疗反应不佳的临床病例。患者接受了硫唑嘌呤(AZA)免疫抑制治疗,并在接受AZA治疗前出现了肝血管瘤,而之前并未检测到肝脏病变。本文讨论了AZA的肝脏医源性问题,以及关于肝血管瘤的病因假说。