DAWSON A M, HOLDSWORTH C D, PITCHER C S
Gut. 1964 Aug;5(4):304-8. doi: 10.1136/gut.5.4.304.
Anaemia due to pyridoxine deficiency has not previously been described in adult coeliac disease. The patient described here had a sideroblastic bone marrow showing the characteristic perinuclear rings of iron-containing granules and biochemical evidence of pyridoxine deficiency. These changes disappeared completely when the patient was put on a gluten-free diet.
此前,成人乳糜泻中尚未有因维生素B6缺乏导致贫血的相关描述。本文所述患者的骨髓呈铁粒幼细胞性,可见含铁颗粒的特征性核周环,且有维生素B6缺乏的生化证据。当患者采用无麸质饮食后,这些变化完全消失。