Ohashi H, Itoh M, Ogawa N, Sudo Y, Endo S, Okugawa T, Ito H, Mineta H, Nozue M
Third Department of Internal Medicine, Hamamatsu University School of Medicine, Japan.
Intern Med. 1992 Sep;31(9):1128-31. doi: 10.2169/internalmedicine.31.1128.
A 38-year-old woman with rheumatoid arthritis who developed Wegener's granulomatosis is described. Wegener's granulomatosis appeared with saddle nose, perforation in her nasal septum, and granuloma in the nasal cavity. Laboratory evaluation showed a positive rheumatoid factor and circulating immune complex. Radiographic examination revealed ankylotic changes in both wrist and elbow joints. Bilateral anosmia and other disease manifestations completely responded to treatment with oral cyclophosphamide and prednisolone.
