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[肾膜的功能]

[The function of kidney membranes].

作者信息

Kinne R

出版信息

Naturwissenschaften. 1977 Jun;64(6):326-34. doi: 10.1007/BF00446787.

DOI:10.1007/BF00446787
PMID:142216
Abstract

Plasma membranes were isolated from rat kidney and their transport properties for sodium, calcium, protons, phosphate, glucose, lactate, and phenylalanine were investigated. The results demonstrate that the luminal plasma membrane, which is in contact with the primary urine, and the contraluminal plasma membrane, which is in contact with the interstitial fluid, differ in their content of ion-sensitive ATPases and sodium-cotransport systems. This allows conclusions on the mechanism of renal transport in which luminal and contraluminal membranes are arranged functionally in series.

摘要

从大鼠肾脏中分离出质膜,并研究了其对钠、钙、质子、磷酸盐、葡萄糖、乳酸盐和苯丙氨酸的转运特性。结果表明,与原尿接触的管腔质膜和与间质液接触的对侧管腔质膜在离子敏感ATP酶和钠共转运系统的含量上有所不同。这使得我们能够对肾脏转运机制得出结论,其中管腔膜和对侧管腔膜在功能上串联排列。

相似文献

1
[The function of kidney membranes].[肾膜的功能]
Naturwissenschaften. 1977 Jun;64(6):326-34. doi: 10.1007/BF00446787.
2
Molecular basis of transepithelial transport in the proximal tubule of rat kidney: properties of the luminal and the contraluminal cell membrane.大鼠肾脏近端小管跨上皮转运的分子基础:管腔和对管腔细胞膜的特性
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Recent advances in the cellular mechanisms and hormonal regulation of urine acidification.
Adv Nephrol Necker Hosp. 1989;18:141-67.
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Membrane-molecular aspects of tubular transport.肾小管转运的膜分子层面
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The polarity of the proximal tubule cell in rat kidney. Different surface charges for the brush-border microvilli and plasma membranes from the basal infoldings.大鼠肾脏近端小管细胞的极性。刷状缘微绒毛和基底褶的质膜具有不同的表面电荷。
J Cell Biol. 1972 Aug;54(2):232-45. doi: 10.1083/jcb.54.2.232.
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[Regulation of the renal excretion of phosphates. Use of isolated vesicles of luminal membranes for the study of phosphate transport].[磷酸盐的肾排泄调节。利用管腔膜分离囊泡研究磷酸盐转运]
Postepy Biochem. 1984;30(3-4):273-94.
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Isolated membrane vesicles in the evaluation of the nature, localization, and regulation of renal transport processes.分离的膜囊泡在评估肾脏转运过程的性质、定位和调节中的应用。
Kidney Int. 1978 Dec;14(6):547-56. doi: 10.1038/ki.1978.163.
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Coupling between proximal tubular transport processes. Studies with ouabain, SITS and HCO3-free solutions.近端肾小管转运过程之间的偶联。哇巴因、SITS和无HCO₃溶液的研究。
Pflugers Arch. 1977 Apr 25;368(3):245-52. doi: 10.1007/BF00585203.

引用本文的文献

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[Molecular weight analysis of physiological proteinuria in newborn infants (author's transl)].新生儿生理性蛋白尿的分子量分析(作者译)
Klin Wochenschr. 1979 Mar 15;57(6):285-91. doi: 10.1007/BF01476510.
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Chemical characterization of human urine albumin in proteinuria.蛋白尿中人类尿白蛋白的化学特征分析。
Experientia. 1979 Mar 15;35(3):316-8. doi: 10.1007/BF01964322.

本文引用的文献

1
CYTOCHEMICAL OBSERVATIONS ON THE RELATIONSHIP BETWEEN LYSOSOMES AND PHAGOSOMES IN KIDNEY AND LIVER BY COMBINED STAINING FOR ACID PHOSPHATASE AND INTRAVENOUSLY INJECTED HORSERADISH PEROXIDASE.通过酸性磷酸酶联合染色及静脉注射辣根过氧化物酶对肾脏和肝脏中溶酶体与吞噬体关系的细胞化学观察
J Cell Biol. 1964 Mar;20(3):497-507. doi: 10.1083/jcb.20.3.497.
2
Characteristics of p-aminohippurate transport in proximal renal tubules.近端肾小管对对氨基马尿酸盐转运的特征
Am J Physiol. 1969 Oct;217(4):1057-63. doi: 10.1152/ajplegacy.1969.217.4.1057.
3
Functions of lysosomes.
溶酶体的功能。
Annu Rev Physiol. 1966;28:435-92. doi: 10.1146/annurev.ph.28.030166.002251.
4
The role of bicarbonate and other buffers on isotonic fluid absorption in the proximal convolution of the rat kidney.碳酸氢盐及其他缓冲剂对大鼠肾脏近端曲管等渗液吸收的作用。
Pflugers Arch. 1971;330(2):149-61. doi: 10.1007/BF00643031.
5
Antiluminal transport of L-arginine and L-leucine following microinjections in pertibular capillaries of the rat.大鼠腮腺毛细血管微量注射后L-精氨酸和L-亮氨酸的抗腔运输
Nephron. 1971;8(4):355-66. doi: 10.1159/000179938.
6
[Protein absorption droplets and lysosomes in the proximal convoluted tubule of the rat kidney. Combined ectronmicroscopic and enzyme-cytochemical studies using intratubular injections with ferritin].[大鼠肾近端曲管中的蛋白质吸收液滴和溶酶体。使用铁蛋白进行肾小管内注射的电子显微镜和酶细胞化学联合研究]
Virchows Arch B Cell Pathol. 1970;5(2):124-43.
7
D-glucose interactions with renal tubule cell surfaces.D-葡萄糖与肾小管细胞表面的相互作用。
Am J Physiol. 1970 Mar;218(3):735-42. doi: 10.1152/ajplegacy.1970.218.3.735.
8
Proximal tubular lactate transport in rat kidney: a micropuncture study.
Kidney Int. 1974 Apr;5(4):261-70. doi: 10.1038/ki.1974.35.
9
Phenomenologic description of Na+, Cl- and HCO-3 absorption from proximal tubules of rat kidney.大鼠肾脏近端小管对Na+、Cl-和HCO-3重吸收的现象学描述。
Pflugers Arch. 1973 Oct 22;343(3):189-220. doi: 10.1007/BF00586045.
10
Sugar transport across the peritubular face of renal cells of the flounder.糖在比目鱼肾小管细胞周缘面的转运。
J Gen Physiol. 1973 Aug;62(2):169-84. doi: 10.1085/jgp.62.2.169.