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[肾膜的功能]

[The function of kidney membranes].

作者信息

Kinne R

出版信息

Naturwissenschaften. 1977 Jun;64(6):326-34. doi: 10.1007/BF00446787.

Abstract

Plasma membranes were isolated from rat kidney and their transport properties for sodium, calcium, protons, phosphate, glucose, lactate, and phenylalanine were investigated. The results demonstrate that the luminal plasma membrane, which is in contact with the primary urine, and the contraluminal plasma membrane, which is in contact with the interstitial fluid, differ in their content of ion-sensitive ATPases and sodium-cotransport systems. This allows conclusions on the mechanism of renal transport in which luminal and contraluminal membranes are arranged functionally in series.

摘要

从大鼠肾脏中分离出质膜,并研究了其对钠、钙、质子、磷酸盐、葡萄糖、乳酸盐和苯丙氨酸的转运特性。结果表明,与原尿接触的管腔质膜和与间质液接触的对侧管腔质膜在离子敏感ATP酶和钠共转运系统的含量上有所不同。这使得我们能够对肾脏转运机制得出结论,其中管腔膜和对侧管腔膜在功能上串联排列。

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