• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

甲基脲和乙酰胺:板鳃亚纲动物肾小管的主动重吸收

METHYLUREA AND ACETAMIDE: ACTIVE REABSORPTION BY ELASMOBRANCH RENAL TUBULES.

作者信息

SCHMIDT-NIELSEN B, RABINOWITZ L

出版信息

Science. 1964 Dec 18;146(3651):1587-8. doi: 10.1126/science.146.3651.1587.

DOI:10.1126/science.146.3651.1587
PMID:14224503
Abstract

The renal tubules of the shark actively reabsorb urea. They also can reabsorb acetamide and methylurea, but there is no evidence for active reabsorption of thiourea. The specificity of the transport system thus appears to be different from the urea secretory system in the frog in which thiourea is secreted but acetamide and methylurea are not secreted.

摘要

鲨鱼的肾小管会主动重吸收尿素。它们也能重吸收乙酰胺和甲基脲,但没有证据表明硫脲会被主动重吸收。因此,这种转运系统的特异性似乎与青蛙的尿素分泌系统不同,在青蛙中,硫脲会被分泌,但乙酰胺和甲基脲不会被分泌。

相似文献

1
METHYLUREA AND ACETAMIDE: ACTIVE REABSORPTION BY ELASMOBRANCH RENAL TUBULES.甲基脲和乙酰胺:板鳃亚纲动物肾小管的主动重吸收
Science. 1964 Dec 18;146(3651):1587-8. doi: 10.1126/science.146.3651.1587.
2
UREA: APPARENT CARRIER-MEDIATED TRANSPORT BY FACILITATED DIFFUSION IN DOGFISH ERYTHROCYTES.
Science. 1964 Apr 3;144(3614):52-3. doi: 10.1126/science.144.3614.52.
3
MECHANISM OF RENAL EXCRETION OF METHYLUREA AND ACETAMIDE IN THE DOG.犬体内甲基脲和乙酰胺的肾脏排泄机制
Am J Physiol. 1965 Jul;209:188-94. doi: 10.1152/ajplegacy.1965.209.1.188.
4
HANDLING OF UREA AND RELATED COMPOUNDS BY THE RENAL TUBULES OF THE FROG.青蛙肾小管对尿素及相关化合物的处理
Am J Physiol. 1963 Sep;205:483-8. doi: 10.1152/ajplegacy.1963.205.3.483.
5
INTRARENAL DISTRIBUTION OF UREA AND RELATED COMPOUNDS: EFFECTS OF NITROGEN INTAKE.尿素及相关化合物的肾内分布:氮摄入的影响。
Am J Physiol. 1964 Nov;207:971-8. doi: 10.1152/ajplegacy.1964.207.5.971.
6
Jack bean urease (EC 3.5.1.5). V. On the mechanism of action of urease on urea, formamide, acetamide, N-methylurea, and related compounds.刀豆脲酶(EC 3.5.1.5)。五、脲酶对尿素、甲酰胺、乙酰胺、N-甲基脲及相关化合物的作用机制
Can J Biochem. 1980 Dec;58(12):1335-44. doi: 10.1139/o80-181.
7
O2 consumption and K+-Na+ balance of elasmobranch kidney slices after replacement of urea by thiourea or acetamide.
Comp Biochem Physiol A Comp Physiol. 1974 Jan;47(1):271-5. doi: 10.1016/0300-9629(74)90070-x.
8
Differential handling of urea and its analogues suggests carrier-mediated urea excretion in freshwater rainbow trout.尿素及其类似物的差异处理表明淡水虹鳟中存在载体介导的尿素排泄。
Physiol Biochem Zool. 2003 Nov-Dec;76(6):791-802. doi: 10.1086/378919.
9
Differential branchial and renal handling of urea, acetamide and thiourea in the gulf toadfish Opsanus beta: evidence for two transporters.海湾蟾鱼(Opsanus beta)鳃和肾对尿素、乙酰胺及硫脲的差异处理:两种转运体的证据
J Exp Biol. 2000 Mar;203(Pt 6):1027-37. doi: 10.1242/jeb.203.6.1027.
10
Permeability of rabbit polymorphonuclear leukocyte membranes to urea and other nonelectrolytes.兔多形核白细胞膜对尿素及其他非电解质的通透性。
Biochim Biophys Acta. 1976 Jun 4;436(1):242-6. doi: 10.1016/0005-2736(76)90235-2.

引用本文的文献

1
The SLC6A18 Transporter Is Most Likely a Na-Dependent Glycine/Urea Antiporter Responsible for Urea Secretion in the Proximal Straight Tubule: Influence of This Urea Secretion on Glomerular Filtration Rate.溶质载体家族6成员18转运体很可能是一种钠依赖性甘氨酸/尿素反向转运体,负责近端直小管中的尿素分泌:这种尿素分泌对肾小球滤过率的影响。
Nephron. 2024;148(11-12):796-822. doi: 10.1159/000539602. Epub 2024 May 31.
2
Effects of the environment on the evolution of the vertebrate urinary tract.环境对脊椎动物泌尿系统进化的影响。
Nat Rev Urol. 2023 Dec;20(12):719-738. doi: 10.1038/s41585-023-00794-3. Epub 2023 Jul 13.
3
Ammonia and urea excretion in the tidepool sculpin (Oligocottus maculosus): sites of excretion, effects of reduced salinity and mechanisms of urea transport.
潮池杜父鱼(Oligocottus maculosus)的氨和尿素排泄:排泄部位、低盐度的影响和尿素转运机制。
Fish Physiol Biochem. 1995 Apr;14(2):111-23. doi: 10.1007/BF00002455.
4
A perfusion study of the handling of urea and urea analogues by the gills of the dogfish shark (Squalus acanthias).狗鲨(Squalus acanthias)鳃对尿素和尿素类似物处理的灌注研究。
PeerJ. 2013 Feb 12;1:e33. doi: 10.7717/peerj.33. Print 2013.
5
The physiology and evolution of urea transport in fishes.鱼类中尿素转运的生理学与进化
J Membr Biol. 2006;212(2):93-107. doi: 10.1007/s00232-006-0869-5. Epub 2007 Jan 30.
6
Evidence for sodium-dependent active urea secretion in the deepest subsegment of the rat inner medullary collecting duct.大鼠肾内髓集合管最深节段中钠依赖性活性尿素分泌的证据。
J Clin Invest. 1998 Jan 15;101(2):423-8. doi: 10.1172/JCI1420.
7
Uphill transport of urea in the dog kidney: effects of certain inhibitors.犬肾中尿素的上坡转运:某些抑制剂的作用
J Clin Invest. 1967 Mar;46(3):388-99. doi: 10.1172/JCI105540.
8
Effect of phloretin on water and solute movement in the toad bladder.根皮素对蟾蜍膀胱水和溶质转运的影响。
J Clin Invest. 1973 Jun;52(6):1435-42. doi: 10.1172/JCI107317.
9
A saturable, vasopressin-sensitive carrier for urea and acetamide in the toad bladder epithelial cell.蟾蜍膀胱上皮细胞中一种对尿素和乙酰胺具有饱和性、血管加压素敏感性的载体。
J Clin Invest. 1973 Aug;52(8):2083-6. doi: 10.1172/JCI107393.