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[溶解的醋酸生育酚对实验性体力负荷耐受性的影响]

[The effect of solubilized alpha-tocopherol acetate on resistance to experimental physical loading].

作者信息

Samoĭlov A V, Seĭfulla R D, Kamaev N O, Tunitskaia T A, Teplova N P, Karmanovskiĭ A Ia, Belous M V

出版信息

Eksp Klin Farmakol. 1992 Mar-Apr;55(2):39-40.

PMID:1422451
Abstract

A single intravenous injection of solubilized alpha-tocopherol acetate to Wistar male rats in doses of 25, 50 and 100 mg/kg noticeably increased the animals' working capacity. The stimulation effect appeared 18 hours after the injection and was observable for two weeks. Utilization of glucose reserves in bioenergy supply of muscle activity has been shown. The maintenance of the action for such a long time may be accounted for by high metabolic stability of solubilized alpha-tocopherol acetate.

摘要

以25、50和100毫克/千克的剂量对雄性Wistar大鼠单次静脉注射溶解的醋酸生育酚,显著提高了动物的工作能力。注射后18小时出现刺激作用,并可持续观察两周。研究表明,肌肉活动的生物能量供应中葡萄糖储备得到了利用。这种作用能维持如此长的时间,可能是由于溶解的醋酸生育酚具有较高的代谢稳定性。

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