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1971年至1988年间,过量服用抗抑郁药对爱尔兰自杀率上升的影响。

The influence of antidepressants in overdose on the increased suicide rate in Ireland between 1971 and 1988.

作者信息

Kelleher M J, Daly M, Kelleher M J

机构信息

St Anne's Hospital & Clinic, Shanakiel, Cork, Ireland.

出版信息

Br J Psychiatry. 1992 Nov;161:625-8. doi: 10.1192/bjp.161.5.625.

DOI:10.1192/bjp.161.5.625
PMID:1422611
Abstract

There has been almost a threefold increase in the incidence of suicide in Ireland during the past 20 years. When each case occurring between 1971 and 1988 was reviewed, the major causes of death were found to be drowning and hanging. Deliberate overdoses with tricyclic antidepressants accounted for less than 4% of all suicides, over the 17 years studied, and during this time, overdose with tricyclics has made a proportionately smaller contribution to the total number of suicides. Greater attention should be paid to identifying and treating the majority of suicidal patients who are at risk by other methods.

摘要

在过去20年里,爱尔兰的自杀率几乎增长了两倍。当对1971年至1988年间发生的每一起自杀案例进行审查时,发现主要死因是溺水和上吊。在研究的17年中,故意过量服用三环类抗抑郁药导致的自杀案例占所有自杀案例的比例不到4%,在此期间,三环类药物过量服用对自杀总数的贡献相对较小。应更加重视识别和治疗大多数有其他自杀风险的患者。

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Suicide in severe depression related to treatment: depressive characteristics and rate of antidepressant overdose.与治疗相关的重度抑郁症中的自杀:抑郁特征及抗抑郁药过量服用率
Eur Arch Psychiatry Clin Neurosci. 2005 Aug;255(4):245-50. doi: 10.1007/s00406-004-0553-7. Epub 2004 Nov 22.
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Association between mortality from suicide in England and antidepressant prescribing: an ecological study.
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BMC Public Health. 2004 Dec 21;4:63. doi: 10.1186/1471-2458-4-63.
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Can the fatal toxicity of antidepressant drugs be predicted with pharmacological and toxicological data?抗抑郁药物的致命毒性能否通过药理学和毒理学数据预测?
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Use of antidepressants among people committing suicide in Sweden.瑞典自杀者中抗抑郁药的使用情况。
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