Lepădat P, Burnea D, Stăncioiu G, Brăileanu A, Galbenu P, Alexandrescu V
Rev Chir Oncol Radiol O R L Oftalmol Stomatol Chir. 1977 May-Jun;26(3):207-15.
The authors have investigated in 6 dogs the disturbances of the perfusion determined by ligature of the main left pulmonary artery, of the pulmonary veins, and mixed ligatures. The scintigraphic method was used (consisting in intravenous injection of radionuclide-labelled ferric colloids, and detection with the Anger camera). In 12 dogs electrocardiographic modifications were also investigated, occuring at various intervals of time after the above-mentioned ligatures. With the aid of scintigraphy it was noted that pulmonary perfusion was abolished in the corresponding lung both immediately and at 24 hours following ligatures. With the aid of scintigraphy it was noted that pulmonary perfusion was abolished in the corresponding lung both immediately and at 24 hours following ligature of the vessels. The same aspects was noted in all three types of ligature. Consecutive infarctions were noted at necropsies. The electrocardiogram evidenced sings of coronary failure when all the pulmonary veins of one lung were ligatured, signs of ventricular and atrial overcharge in dogs with ligature of the pulmonary artery and mixed modifications, although less severe, in combined vascular ligatures. The more rapid evolution toward death of dogs with ligatures of the pulmonary veins could be explained by the coronary failure.
作者对6只犬进行了研究,通过结扎左肺动脉主干、肺静脉以及混合结扎来确定灌注紊乱情况。采用了闪烁扫描法(包括静脉注射放射性核素标记的铁胶体,并使用安杰尔相机进行检测)。还对12只犬在上述结扎后的不同时间间隔出现的心电图改变进行了研究。借助闪烁扫描法发现,在结扎血管后,相应肺脏的肺灌注立即以及在24小时时均被消除。在所有三种结扎类型中均观察到相同情况。尸检时发现了连续性梗死。当一侧肺的所有肺静脉被结扎时,心电图显示出冠状动脉衰竭的迹象;在结扎肺动脉和混合结扎的犬中,出现心室和心房负荷过重的迹象,尽管在联合血管结扎时程度较轻。肺静脉结扎的犬向死亡发展更快可由冠状动脉衰竭来解释。