Blume W T, Jones D C, Young G B, Girvin J P, McLachlan R S
University Hospital, University of Western Ontario, London, Canada.
Brain. 1992 Oct;115 ( Pt 5):1509-20. doi: 10.1093/brain/115.5.1509.
Five patients with seizures involving the secondary sensory and/or related areas (SSRA) are presented. Four of five experienced ictal numbness and/or tingling bilaterally and/or axially; this involved fingertips (three patients), lips (two), tongue (two), and was diffuse in one. The fifth patient experienced bilateral ictal pain. Associated ictal symptoms implicating adjacent regions appeared in all five patients, including contralateral clonic movements (two patients), hypersalivation (two), taste (one), vocalization (two), dysphagia (one), and contralateral sensory march (one). Two patients had ictal symptoms suggestive of adjacent temporal lobe involvement. By history, the SSRA was involved at seizure onset in four and by spread in one. All five patients had electroencephalogram (EEG) or subdural EEG supportive evidence of SSRA involvement: ictal (three) and interictal (three). Three patients had lesions in this area shown by magnetic resonance imaging or computerized tomography and all three had histologically proven glial tumours. Relevant experimental physiological and anatomical data are reviewed.
本文报告了5例发作累及二级感觉和/或相关区域（SSRA）的患者。5例患者中有4例在发作期出现双侧和/或轴向的麻木和/或刺痛；累及指尖（3例患者）、嘴唇（2例）、舌头（2例），1例为弥漫性。第5例患者发作期出现双侧疼痛。所有5例患者均出现累及相邻区域的相关发作期症状，包括对侧阵挛性运动（2例患者）、流涎过多（2例）、味觉（1例）、发声（2例）、吞咽困难（1例）和对侧感觉性扩散（1例）。2例患者的发作期症状提示相邻颞叶受累。根据病史，4例患者发作起始时累及SSRA，1例为扩散累及。所有5例患者的脑电图（EEG）或硬膜下EEG均有SSRA受累的支持证据：发作期（3例）和发作间期（3例）。3例患者经磁共振成像或计算机断层扫描显示该区域有病变，且所有3例均经组织学证实为胶质瘤。本文对相关的实验生理和解剖数据进行了综述。
