TRUSLER G A, MUSTARD W T, FOWLER R S
Can Med Assoc J. 1964 Nov 21;91(21):1096-100.
In 28 infants and children with complete transposition of the great vessels, atrial septal defects were created utilizing an open technique with inflow caval occlusion and moderate hypothermia. Of the 12 infants for whom operation was necessary during the first two weeks of life only two survived, suggesting that this technique is not adequate for infants at this age. Only four of the 16 children operated on between the ages of two weeks and three years failed to survive. Two of these died because of pre-existing non-cardiac conditions. Seven children with associated systemic-to-pulmonary shunts survived; the open technique may be preferable in this particular group. Despite the initial improvement afforded by this procedure, three sudden late deaths occurred. For this reason, and because of the danger of early development of pulmonary vascular disease, total operative correction of the malformation should be performed early.
在28例患有完全性大动脉转位的婴幼儿中,采用开放技术并阻断腔静脉回流及中度低温的方法制造房间隔缺损。在出生后前两周内必须接受手术的12例婴儿中,仅2例存活,这表明该技术对这个年龄段的婴儿并不适用。在两周至三岁之间接受手术的16例儿童中,只有4例未能存活。其中2例因术前存在非心脏疾病而死亡。7例伴有体肺分流的儿童存活;在这一特定群体中,开放技术可能更可取。尽管该手术最初带来了病情改善,但仍发生了3例晚期猝死。基于这个原因,并且由于早期发生肺血管疾病的风险,应尽早对该畸形进行完全手术矫正。