Petrelli C, Moretti P, Petrelli F, Bramucci M
Department of Molecular, Cellular and Animal Biology, University of Camerino, Italy.
Cell Biol Int Rep. 1992 Oct;16(10):967-74. doi: 10.1016/s0309-1651(06)80049-4.
The peptide isolated by us from calf pineal gland causes a reduction of RNA synthesis in vitro in L1210 and HL60 tumoral cells. This peptide also causes inhibition of cell proliferation; the cell viability is not modified. The effects are dose-dependent and reversible.
我们从小牛松果体中分离出的肽在体外可使L1210和HL60肿瘤细胞中的RNA合成减少。这种肽还会抑制细胞增殖；细胞活力未发生改变。这些作用具有剂量依赖性且是可逆的。
