Sugimura K, Kuroda S, Furukawa T, Matsuda S, Yoshimura Y, Ishida T
Department of Radiology, Shimane Medical University, Enya Izumo, Japan.
Clin Radiol. 1992 Oct;46(4):243-7. doi: 10.1016/s0009-9260(05)80163-1.
We examined the usefulness of MRI in differentiating post-radiation scar tissue from the residual tumour. Ten consecutive patients who underwent MR imaging before and after radiation therapy were assessed prospectively. T1- and T2-weighted images using a 1.5 unit were obtained in 10 patients (3 T1, 6 T2, 1 T3) at 1 week before irradiation, and 2 weeks, 2 months, 4 months, 6 months and every 6 months thereafter following completion of radiation. Although all T2 and T3 tumours demonstrated high signal intensity compared to muscle on T2-weighted images, the T1 tumour could be demonstrated in only one of three patients. Six patients in whom the primary tumour clinically disappeared demonstrated low signal intensity on T2-weighted images until 4 months after completion of radiation therapy (range 1 week to 4 months). This study suggests that MRI can detect primary tumours larger than T2 (2 cm), and may be useful in assessing the effectiveness of therapy for tongue cancer.
我们研究了磁共振成像（MRI）在区分放疗后瘢痕组织与残留肿瘤方面的实用性。对连续10例放疗前后均接受磁共振成像检查的患者进行了前瞻性评估。10例患者（3例T1期、6例T2期、1例T3期）在放疗前1周以及放疗结束后2周、2个月、4个月、6个月及之后每6个月，使用1.5单位设备获取了T1加权像和T2加权像。尽管所有T2期和T3期肿瘤在T2加权像上与肌肉相比均表现为高信号强度，但T1期肿瘤仅在3例患者中的1例中显示出来。6例临床诊断原发性肿瘤消失的患者在放疗结束后4个月（范围为1周～4个月）内，T2加权像上显示为低信号强度。本研究表明，MRI能够检测出大于T2期（2 cm）的原发性肿瘤，并且可能有助于评估舌癌的治疗效果。
