Willershausen-Zönnchen B, Zimmermann M, Defregger A, Schramel P, Hamm G
Poliklinik für Zahnerhaltung und Parodontologie, Universität München.
Dtsch Med Wochenschr. 1992 Nov 13;117(46):1743-7. doi: 10.1055/s-2008-1062504.
Mercury concentrations were measured in specimens of oral mucosa taken during oral surgery from 90 patients (53 men, 37 women, mean age 42 +/- 16 years); 30 of the patients had no amalgam fillings. All the mucosal specimens extended for at least 2-3 mm from the epithelium of the gingival margin and were clinically and radiologically normal. Thirteen patients without metallic fillings of any kind had mercury concentrations of 118.4 +/- 83.7 ng/g tissue, and in 17 patients with precious metal fillings but no amalgam the mean mercury concentrations were 144 +/- 290 ng/g tissue. Seventeen patients with 1-3 amalgam fillings had an average of 1975 +/- 4300 ng/g tissue and in 26 patients with 3-6 amalgam fillings the average concentration was 1158 +/- 2500 ng/g tissue. In 17 patients with more than six amalgam fillings the mean mercury concentration was 2302 +/- 5600 ng/g tissue. Although these results demonstrate a considerable degree of transfer of mercury from the amalgam fillings to the oral mucosa, it had not resulted in any clinically detectable mucosal lesions.
在口腔外科手术中，对90例患者（53名男性，37名女性，平均年龄42±16岁）的口腔黏膜标本进行了汞浓度测量；其中30例患者没有汞合金填充物。所有黏膜标本均从牙龈边缘上皮延伸至少2 - 3毫米，临床和放射学检查均正常。13例无任何金属填充物的患者，其组织汞浓度为118.4±83.7纳克/克，17例有贵金属填充物但无汞合金的患者，平均汞浓度为144±290纳克/克。17例有1 - 3颗汞合金填充物的患者，平均为1975±4300纳克/克，26例有3 - 6颗汞合金填充物的患者，平均浓度为1158±2500纳克/克。17例有超过6颗汞合金填充物的患者，平均汞浓度为2302±5600纳克/克。虽然这些结果表明汞从汞合金填充物向口腔黏膜有相当程度的转移，但尚未导致任何临床可检测到的黏膜病变。
