Moniz de Bettencourt J, Carvalho J S, Pinto B G, Pimentao J B
C R Seances Soc Biol Fil. 1977;171(2):329-32.
On the carotid reflexogenic zone lobeline provoques : 1) a increase of amplitude and rate of respiratory movements with bradycardia and hypotension ; 2) a secondary decrease of amplitude and rate of breathing with tachycardia. Acting on the reflexogenic zone, phentolamine and dibenamine provoque a transitory weakening or disappearance of these reflexes. These effects are induced by a local action, because they are not observed by intravenous injection of the drugs and the lobeline reflexes starting from the carotid sinus of the other side are not affected.