Cambar J, Piquet Y, Mesnier F, Canellas J
C R Seances Soc Biol Fil. 1977;171(2):355-60.
We have prepared in rabbits antibodies against rat GBM, with GBM prepared from isolated glomeruli issued from rat renal cortex. It is shown with immunodiffusion technique the excretion of basement membrane-like fragments into the normal rat urine. This result confirms the earlier works studying the human and rabbit urines. The origin and the nature of this patterns, the signification of this presence into the mammalian urines are discussed.
我们用从大鼠肾皮质分离的肾小球制备的肾小球基底膜(GBM),在兔体内制备了抗大鼠GBM抗体。免疫扩散技术显示,正常大鼠尿液中有基底膜样片段排出。这一结果证实了早期对人类和兔尿液的研究。本文讨论了这种模式的起源和性质,以及其在哺乳动物尿液中存在的意义。