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唾液的激肽形成和破坏活性

KININ-FORMING AND DESTROYING ACTIVITIES OF SALIVA.

作者信息

AMUNDSEN E, NUSTAD K

出版信息

Br J Pharmacol Chemother. 1964 Dec;23(3):440-4. doi: 10.1111/j.1476-5381.1964.tb01600.x.

Abstract

Kininase activity is present in saliva obtained from the oral cavity but not in saliva obtained by cannulation of the parotid or submandibular ducts. This activity originates from squamous epithelial cells from the oral mucous membranes. Experiments with various inhibitors indicated that the kininase activity of squamous epithelial cells differs from that of plasma, and resembles that of erythrocytes. Kinin-forming activity is present both in the glandular secretion and in the squamous epithelial cells.

摘要

激肽酶活性存在于从口腔获取的唾液中,但不存在于通过腮腺或下颌下腺导管插管获取的唾液中。这种活性源自口腔黏膜的鳞状上皮细胞。用各种抑制剂进行的实验表明,鳞状上皮细胞的激肽酶活性与血浆不同,与红细胞的激肽酶活性相似。激肽形成活性既存在于腺分泌液中,也存在于鳞状上皮细胞中。

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引用本文的文献

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Kinin-forming and destroying activities of cell homogenates.细胞匀浆的激肽形成和破坏活性。
J Physiol. 1965 Aug;179(3):479-88. doi: 10.1113/jphysiol.1965.sp007674.
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In vitro studies on the mechanism of kinin formation by trypanosomes.锥虫形成激肽机制的体外研究。
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本文引用的文献

1
The estimation of urinary kallkrein.尿激肽释放酶的测定
J Physiol. 1959 Oct;148(2):267-82. doi: 10.1113/jphysiol.1959.sp006287.
2
KINIRASE ACTIVITY OF HUMAN SALIVA.
Nature. 1964 Mar 21;201:1226-7. doi: 10.1038/2011226a0.
3
A STABLE SUBSTRATE FOR THE ASSAY OF PLASMA KININ-FORMING ENZYMES.用于测定血浆激肽形成酶的稳定底物。
Br J Pharmacol Chemother. 1963 Dec;21(3):500-8. doi: 10.1111/j.1476-5381.1963.tb02018.x.
4
[Recent results in the field of plasma kinins].[血浆激肽领域的近期研究成果]
Klin Wochenschr. 1963 Apr 1;41:297-311. doi: 10.1007/BF01484325.
5
Active polypeptides derived from plasma proteins.源自血浆蛋白的活性多肽。
Physiol Rev. 1960 Oct;40:647-76. doi: 10.1152/physrev.1960.40.4.647.

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