血红蛋白F德州型：γ链变体
HEMOGLOBIN F TEXAS: GAMMA-CHAIN VARIANT.
作者信息
SCHNEIDER R G, JONES R T
出版信息
Science. 1965 Apr 9;148(3667):240-2. doi: 10.1126/science.148.3667.240.
PMID:14259765
Abstract
An abnormal fetal hemoglobin, designated hemoglobin F(Texas), was found in the cord blood of five Negro infants (all related and three of them siblings) and of one Caucasian infant. Studies on the chemical structure of this variant indicate that there is a substitution of a lysyl residue for either the fifth or sixth glutamyl residue of the gamma-chain.
摘要
在五名黑人婴儿（均有亲属关系，其中三名是兄弟姐妹）和一名白人婴儿的脐带血中发现了一种异常胎儿血红蛋白，命名为血红蛋白F（德克萨斯型）。对这种变体化学结构的研究表明，γ链的第五或第六个谷氨酰残基被一个赖氨酰残基取代。
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