FILO R S, BOHR D F, RUEGG J C
Science. 1965 Mar 26;147(3665):1581-3. doi: 10.1126/science.147.3665.1581.
Contractions of glycerinated skeletal (striated) and vascular (smooth) muscles are similar in their calcium dependence but differ in their magnesium dependence. The threshold concentration of free Ca(++) for contraction of either muscle was 1.8 x 10(-7)M; maximum tension developed when the concentration of free Ca(++) was slightly greater than 10(-6)M. The Mg concentration required for contraction of smooth muscle was at least ten times as great as that for skeletal muscle.
甘油处理的骨骼肌（横纹肌）和血管平滑肌的收缩在对钙的依赖性方面相似，但在对镁的依赖性方面有所不同。两种肌肉收缩时游离Ca(++)的阈值浓度均为1.8×10(-7)M；当游离Ca(++)浓度略高于10(-6)M时产生最大张力。平滑肌收缩所需的镁浓度至少是骨骼肌的十倍。
