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Cardiac glycosides: prerequisites for the development of new cardiotonic compounds.

作者信息

Güntert T W, Linde H H

出版信息

Experientia. 1977 Jun 15;33(6):697-703. doi: 10.1007/BF01944136.

DOI:10.1007/BF01944136

PMID:142642

Abstract

摘要

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Cardiac glycosides: prerequisites for the development of new cardiotonic compounds.

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本文引用的文献

[ATTEMPT AT AN ANALYSIS OF THE RELATIONSHIP BETWEEN CHEMICAL STRUCTURE AND DIGITALIS-LIKE ACTIVITY ON THE RECEPTOR LEVEL].

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DIGITALIS ACTION ON THE CELLS: FABLE, FACT, AND FANCY.

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Toxic effects of ouabain on Purkinje fibers and ventricular muscle fibers.

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Synthesis of 15-beta-hydroxydigitoxigenin.

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Modified cardenolides. II. Synthesis, NMR spectra, and biological activity of C-19 halides and sulfonates.

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Cardiac glycosides and aglycones by synthesis and microbiological conversion.

J Med Chem. 1965 Sep;8(5):577-9. doi: 10.1021/jm00329a006.

A new finding about the structure-activity relationship of cardiotonic steroids: lack of cardiotonic action in 15 alpha-hydroxydigitoxigenin.

Experientia. 1964 Oct 15;20(10):572-3. doi: 10.1007/BF02150301.

[Influence of the 16-hydroxyl groups on the action of cardenolides. The inotropic action of 16-epi-gitoxigenin].

Experientia. 1964 May 15;20(5):263-4. doi: 10.1007/BF02151795.

Synthesis and biological activity of the ketals of digitoxigenone and digoxigenone and some acetals of digitoxigenin and digoxigenin.

J Pharm Sci. 1969 Feb;58(2):228-31. doi: 10.1002/jps.2600580220.

Cardiotonic activities of 4 new compounds derived from digitoxigenin and uzarigenin, and their structure-activity relationship.

Experientia. 1968 May 15;24(5):466-7. doi: 10.1007/BF02144395.

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