由洋地黄毒苷元和乌沙苷元衍生的4种新化合物的强心活性及其构效关系。 - Suppr

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Cardiotonic activities of 4 new compounds derived from digitoxigenin and uzarigenin, and their structure-activity relationship.

作者信息

Shigei T, Mineshita S

出版信息

Experientia. 1968 May 15;24(5):466-7. doi: 10.1007/BF02144395.

DOI:10.1007/BF02144395

PMID:5674987

Abstract

摘要

相似文献

Cardiotonic activities of 4 new compounds derived from digitoxigenin and uzarigenin, and their structure-activity relationship.由洋地黄毒苷元和乌沙苷元衍生的4种新化合物的强心活性及其构效关系。

Experientia. 1968 May 15;24(5):466-7. doi: 10.1007/BF02144395.

Cardiotonic action of 3-deoxydigitoxigenin.3-去氧洋地黄毒苷元的强心作用。

Experientia. 1970 Aug 15;26(8):867-8. doi: 10.1007/BF02114228.

Cardiotonic activities of 3,5-seco-4-nor-cardenolides in Rana nigromaculata.黑斑蛙中3,5-断-4-去甲强心甾类化合物的强心活性

Experientia. 1975 Aug 15;31(8):955-6. doi: 10.1007/BF02358874.

Cardiotonic activities of some new type of bufadienolide- and cardenolide-conjugates.某些新型蟾蜍二烯羟酸内酯和强心甾烯糖苷缀合物的强心活性

Experientia. 1977 Feb 15;33(2):258-60. doi: 10.1007/BF02124098.

Structure-activity relationship of the cardenolides derived from digoxigenin and digitoxigenin, with special reference to the configuration at C-5.洋地黄毒苷元和地芰毒苷元衍生的强心苷的构效关系，特别涉及C-5位的构型

Experientia. 1974 Nov 15;30(11):1308-10. doi: 10.1007/BF01945201.

[On interactions between digitoxigenin, noradrenaline and calcium on the myocardium].

Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;260(2):188-9.

Cardenolide analogs. V. Cardiotonic activity of semisynthetic analogs of digitoxigenin.强心甾内酯类似物。V. 洋地黄毒苷元半合成类似物的强心活性。

J Pharmacol Exp Ther. 1974 Nov;191(2):219-31.

[Interaction of digitoxigenin, norepinephrine and calcium during hypothermia in isolated mammalina heart preparations].

Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1968;261(3):191-211.

[Ca-dependent changes in membrane potential and cardiac contraction under the influence of adrenaline and digitoxigenin].

Naunyn Schmiedebergs Arch Pharmakol. 1970;266(4):445-6.

Insusceptibility to the action of cardiotonic steroids of the "slow muscle fibre system" of the toad.蟾蜍“慢肌纤维系统”对强心甾类作用不敏感。

Experientia. 1970 Sep 26;26(9):987-8. doi: 10.1007/BF02114147.

引用本文的文献

Structure-activity relationship of the cardenolide, with special reference to the substituents and configurations at C-14 and C-15.强心甾内酯的构效关系，特别涉及C-14和C-15位的取代基及构型

Experientia. 1973 Apr 15;29(4):449-50. doi: 10.1007/BF01926775.

Experientia. 1974 Nov 15;30(11):1308-10. doi: 10.1007/BF01945201.

Relationship between the potentiation of potassium-induced contracture of cardiac muscle by four cardenolides and their inhibitory effects on the sodium potassium activated adenosine triphosphatase of brain.

Experientia. 1971 Apr 15;27(4):415-6. doi: 10.1007/BF02137284.

Cardiotonic activities of 3,5-seco-4-nor-cardenolides in Rana nigromaculata.黑斑蛙中3,5-断-4-去甲强心甾类化合物的强心活性

Experientia. 1975 Aug 15;31(8):955-6. doi: 10.1007/BF02358874.

Cardiac glycosides: prerequisites for the development of new cardiotonic compounds.强心苷：新型强心化合物研发的先决条件。

Experientia. 1977 Jun 15;33(6):697-703. doi: 10.1007/BF01944136.

本文引用的文献

A STUDY ON THE STRUCTURE-ACTIVITY RELATIONSHIP OF THE CARDIOTONIC STEROIDS.强心甾体类化合物构效关系的研究

Jpn J Pharmacol. 1965 Mar;15:62-71. doi: 10.1254/jjp.15.62.

Synthesis of 15-beta-hydroxydigitoxigenin.

Chem Pharm Bull (Tokyo). 1967 Mar;15(3):352-3.

A new finding about the structure-activity relationship of cardiotonic steroids: lack of cardiotonic action in 15 alpha-hydroxydigitoxigenin.

Experientia. 1964 Oct 15;20(10):572-3. doi: 10.1007/BF02150301.

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