BOARD J A
Can Med Assoc J. 1965 Apr 10;92(15):814-7.
Norethindrone 5 mg. plus mestranol 0.075 mg., taken daily from menstrual cycle day five through day 24, was used as an oral contraceptive agent in 1248 cycles by 132 clinic patients. One hundred and one patients used this method for six months or more. There were no unplanned pregnancies. Breakthrough bleeding occurred in 38 cycles (3.0% of all cycles). In 25% of 1201 cycles the duration of menstrual flow was shorter than that which had been considered usual for the individual patient involved, and the most common weight change was a gain of 6 to 10 lb.
炔诺酮5毫克加炔雌醇甲醚0.075毫克,从月经周期第5天至第24天每日服用,132名门诊患者在1248个周期中用作口服避孕药。101名患者使用该方法达6个月或更长时间。无意外妊娠发生。突破性出血发生在38个周期(占所有周期的3.0%)。在1201个周期中,25%的月经持续时间短于相关个体患者以往的正常经期,最常见的体重变化是增加6至10磅。