CROCKER K M, STITT W D
Can Med Assoc J. 1964 Mar 21;90(12):713-6.
One hundred and eighty-five women were followed up for periods up to 15 months (a total of 964 menstrual cycles) to determine the contraceptive efficacy and side effects of 2 mg. norethindrone with 0.1 mg. mestranol, as well as other therapeutic benefits. No pregnancies occurred in those using this method alone for contraception. Side effects were minimal. This low dosage was also useful in the management of dysmenorrhea, menorrhagia and irregular menses.
185名女性接受了长达15个月的随访（共计964个月经周期），以确定2毫克炔诺酮与0.1毫克炔雌醇的避孕效果、副作用以及其他治疗益处。单独使用这种方法避孕的女性没有怀孕。副作用微乎其微。这种低剂量在治疗痛经、月经过多和月经不调方面也很有效。
