Amarapurkar D N, Kumar A, Vaidya S, Murti P, Bichile S K, Kalro R H, Desai H G
Department of Gastroenterology, BYL Nair Ch Hospital, Bombay.
Indian J Gastroenterol. 1992 Apr;11(2):80-1.
Of forty multi-transfused thalassemia patients (26 males, 14 females; mean age 8.1 +/- 5.3 years, range 1-35) with no clinical or biochemical evidence of liver disease, HBsAg, anti-hepatitis C virus and anti-human immunodeficiency virus antibodies were present in 18 (45%), 7 (17.5%) and 1 (2.5%) cases respectively. Three of the 18 (16.7%) HBsAg positive patients were anti-delta antibody positive. Our results indicate that more than 50% of multi-transfused thalassemia patients show serological evidence of one or more of hepatitis B, C and D and human immunodeficiency virus infection.
在40例多次输血的地中海贫血患者中（26例男性，14例女性；平均年龄8.1±5.3岁，范围1 - 35岁），无肝脏疾病的临床或生化证据，分别有18例（45%）、7例（17.5%）和1例（2.5%）存在乙肝表面抗原（HBsAg）、抗丙型肝炎病毒抗体和抗人类免疫缺陷病毒抗体。18例HBsAg阳性患者中有3例（16.7%）抗丁型肝炎抗体阳性。我们的结果表明，超过50%的多次输血的地中海贫血患者显示出感染乙型、丙型和丁型肝炎病毒及人类免疫缺陷病毒中一种或多种的血清学证据。
