Chadha S L, Gopinath N, Ramachandran K
Sitaram Bhartia Institute of Science & Research, New Delhi.
Indian J Med Res. 1992 Apr;96:115-21.
A community based survey of coronary heart disease (CHD) was carried out in Gujarati families settled in Delhi. The number of adults surveyed in the age group 25-64 yr was 1317. CHD was diagnosed either on the basis of clinical history supported by documentary evidence of treatment in the hospital or at home or on ECG evidence in accordance with the Minnesota Code. The prevalence rate of CHD on clinical history was 25.1 (28.2 in males and 22.4 in females) per 1000 adults (25-64 yr). The prevalence rates were slightly lower in Gujaratis than the general Delhi urban population. The prevalence rate based on both clinical history and ECG criteria was estimated at 66.8 as compared to 96.8/1000 in general urban Delhi population. The risk factors for CHD such as socio-economic status, family history, obesity, smoking, physical activity and hypertension were studied. The mean and 5th, 50th and 95th percentile values of blood lipids were also estimated in CHD patients and compared with the control group. Hypertension ranked the leading risk factor. Prevalence rate of CHD was higher in the upper socioeconomic group. The positive correlation of higher levels of serum lipids e.g., total cholesterol, low density lipoprotein cholesterol (LDL-C) and triglyceride with CHD was confirmed.
在定居于德里的古吉拉特族家庭中开展了一项基于社区的冠心病（CHD）调查。调查的25 - 64岁成年人数量为1317人。冠心病的诊断依据为：有在医院或家中接受治疗的书面证据支持的临床病史，或依据明尼苏达编码的心电图证据。基于临床病史的冠心病患病率为每1000名成年人（25 - 64岁）中25.1例（男性为28.2例，女性为22.4例）。古吉拉特族的患病率略低于德里城市总人口。基于临床病史和心电图标准的患病率估计为66.8/1000，而德里城市总人口的患病率为96.8/1000。对冠心病的危险因素，如社会经济地位、家族史、肥胖、吸烟、体力活动和高血压进行了研究。还对冠心病患者的血脂均值以及第5、第50和第95百分位数进行了估计，并与对照组进行了比较。高血压是首要危险因素。社会经济地位较高群体的冠心病患病率更高。血清脂质水平升高，如总胆固醇、低密度脂蛋白胆固醇（LDL - C）和甘油三酯与冠心病的正相关性得到了证实。
