IMMUNOFLUORESCENCE OF FELINE PANLEUCOPENIA VIRUS IN CELL CULTURE: DETERMINATION OF IMMUNOLOGICAL STATUS OF FELINES BY SERUM NEUTRALIZATION.

Utilizing specific immunofluorescence as a viral indicator for a cell culture serum-neutralization system, the authors were able to demonstrate a relationship between specific antibody titer and susceptibility of felines to feline panleucopenia virus. This correlation was established by comparing prechallenge serum-neutralization titers to the clinical response of felines challenged with feline panleucopenia virus. The serological and clinical response of felines inoculated with commercial vaccines or related viruses was also studied.