MILHORN H T, BENTON R, ROSS R, GUYTON A C
Biophys J. 1965 Jan;5(1):27-46. doi: 10.1016/s0006-3495(65)86701-7.
The respiratory system exhibits the properties of a control system of the regulator type. Equations describing this biological control system have been derived. Transient and steady-state solutions for various CO(2) and O(2) step input disturbances were obtained utilizing a digital computer and are compared with experimental results. The effectiveness of the respiratory system as a regulator is investigated. Further extensions of the model are suggested.
呼吸系统具有调节型控制系统的特性。描述这个生物控制系统的方程已经推导出来。利用数字计算机获得了各种二氧化碳和氧气阶跃输入干扰下的瞬态和稳态解,并与实验结果进行了比较。研究了呼吸系统作为调节器的有效性。还提出了该模型的进一步扩展。