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[采用手术方法对小鼠心肌病理学进行建模]

[Modeling of myocardial pathology in mice with the surgical methods].

作者信息

Kogan M E, Belov L N, Leont'eva T A, Zolotareva A G

出版信息

Kardiologiia. 1977 Jun;17(6):125-8.

PMID:142856
Abstract

A description of three operations on the heart in mice is presented: a supravalvular narrowing of the ascending aorta, banding of the apex of the heart, and ligation of the coronaries. These surgical interventions permit to obtain in mice a functional overloading and hypertrophy of the myocardium, a cardiac aneurysm and occlusive myocardial infarction.

摘要

本文介绍了对小鼠心脏进行的三种手术操作

升主动脉瓣上缩窄、心脏心尖环扎和冠状动脉结扎。这些手术干预可使小鼠出现心肌功能过载和肥厚、心脏动脉瘤以及闭塞性心肌梗死。

相似文献

1
[Modeling of myocardial pathology in mice with the surgical methods].[采用手术方法对小鼠心肌病理学进行建模]
Kardiologiia. 1977 Jun;17(6):125-8.
2
Mouse cardiac surgery: comprehensive techniques for the generation of mouse models of human diseases and their application for genomic studies.小鼠心脏手术：构建人类疾病小鼠模型的综合技术及其在基因组研究中的应用
Physiol Genomics. 2004 Feb 13;16(3):349-60. doi: 10.1152/physiolgenomics.00041.2003.
3
Resection of postinfarction ventricular aneurysms and simultaneous myocardial revascularization.心肌梗死后室壁瘤切除术及同期心肌血运重建术。
J Cardiovasc Surg (Torino). 1969 Nov-Dec;10(6):419-25.
4
Production of experimental occlusive myocardial infarction in mice.在小鼠中制造实验性闭塞性心肌梗死。
Cor Vasa. 1978;20(4):308-14.
5
Polyarteritis nodosa in the adult. Report of a case with repeated myocardial infarction and a review of cardiac involvement.成人结节性多动脉炎。一例反复心肌梗死病例报告及心脏受累情况综述。
S Afr Med J. 1981 Sep 26;60(13):512-8.
6
[Reproduction of heart aneurysm in dogs by means of inhibiting regenerative processes in the course of experimental infarct].[通过抑制实验性梗死过程中的再生过程在犬中复制心脏动脉瘤]
Eksp Khir Anesteziol. 1972 Mar-Apr;17(2):14-6.
7
Surgical treatment of coronary artery disease.冠状动脉疾病的外科治疗
Ariz Med. 1971 May;28(5):363-70.
8
[Surgical treatment of coronary insufficiency. Current aspects. II].[冠状动脉供血不足的外科治疗。当前进展。II]
Arq Bras Cardiol. 1971 Oct;24(5):57-64.
9
[Ventricular aneurysm after postero-lateral myocardial infarct: excision and aorta-right coronary venous bridging].[后外侧心肌梗死后室壁瘤：切除及主动脉 - 右冠状动脉静脉搭桥术]
Ann Chir Thorac Cardiovasc. 1970 Jul;9(3):287-92.
10
[Left ventricular aneurysm caused by thrombosis of the anterior interventricular artery. Exeresis and right aorto-coronary anastomosis].[前室间动脉血栓形成导致的左心室动脉瘤。切除术及右主动脉-冠状动脉吻合术]
Presse Med (1893). 1971 Jul 3;79(33):1499-500.

引用本文的文献

1
Mouse models of myocardial infarction: comparing permanent ligation and ischaemia-reperfusion.心肌梗死的小鼠模型：比较永久性结扎和缺血再灌注。
Dis Model Mech. 2020 Nov 18;13(11):dmm046565. doi: 10.1242/dmm.046565.
2
Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling.血管活性因子 Wisp-1 在心肌梗死中增加，并调节心脏内皮信号转导。
JCI Insight. 2018 Feb 22;3(4). doi: 10.1172/jci.insight.95824.
3
Coronary artery ligation and intramyocardial injection in a murine model of infarction.在小鼠梗死模型中进行冠状动脉结扎和心肌内注射。
J Vis Exp. 2011 Jun 7(52):2581. doi: 10.3791/2581.