Bahmer F A
Hautklinik, Universität des Saarlandes, Homburg/Saar.
Hautarzt. 1992 Oct;43(10):625-8.
For X-ray therapy, the relation between single doses, number of fractions and duration of therapy have been combined in the TDF (time, dose, fraction) factor by Orton and Ellis. This factor seems to be well suited to evaluation of the X-ray therapy of basal cell carcinomas and squamous cell carcinomas of the skin. A simplified TDF formula is presented, together with some methods of calculation. Furthermore, tables are presented containing TDF values for frequently applied single doses and for two to five fractions per week. In addition, some hints are given on the use of the decay factor of Orton and Ellis to compensate for the loss of X-ray effectiveness if therapy has been interrupted.
对于X射线治疗,奥顿和埃利斯将单次剂量、分次次数和治疗持续时间之间的关系整合到了TDF(时间、剂量、分次)因子中。该因子似乎非常适合用于评估皮肤基底细胞癌和鳞状细胞癌的X射线治疗。本文给出了一个简化的TDF公式以及一些计算方法。此外,还列出了表格,其中包含常用单次剂量以及每周两至五次分次的TDF值。另外,还给出了一些关于使用奥顿和埃利斯衰变因子的提示,以便在治疗中断时补偿X射线有效性的损失。