Davis S L, Barse F, Meoli F G
Department of Surgery, University of Medicine and Dentistry of New Jersey, School of Osteopathic Medicine, Stratford.
J Am Osteopath Assoc. 1992 Aug;92(8):1005-6, 1013-6.
Male breast cancer is difficult to study because it occurs infrequently, accounting for 1% of all breast carcinoma. Breast cancer occurs 10 years later in men than in women, and its presentation parallels that in women. The authors retrospectively review 13 cases of male breast cancer occurring over a 20-year period in four community hospitals. Treatment methods paralleled those used for female cancer patients. Surgery, primarily radical mastectomy, was performed in all patients. In the eight patients in whom hormone receptor assays were obtained, all tests were positive for estrogen receptors, progesterone receptors, or both. Metastases were diagnosed in five patients during follow-up. The longest disease-free survival has been 10 years. Similarities and differences regarding male and female breast cancer are discussed as are the diagnosis and management of men with this disease.
男性乳腺癌难以研究,因为其发病率低,仅占所有乳腺癌的1%。男性患乳腺癌的时间比女性晚10年,其临床表现与女性相似。作者回顾性分析了4家社区医院在20年期间发生的13例男性乳腺癌病例。治疗方法与女性癌症患者所用方法相似。所有患者均接受了手术,主要是根治性乳房切除术。在8例进行了激素受体检测的患者中,所有检测的雌激素受体、孕激素受体或两者均呈阳性。随访期间有5例患者被诊断为转移。最长无病生存期为10年。本文讨论了男性和女性乳腺癌的异同,以及男性乳腺癌的诊断和治疗。