腺嘌呤增强乙硫氨酸对鼠伤寒沙门氏菌的抑制作用。
ENHANCEMENT BY ADENINE OF THE INHIBITION OF SALMONELLA TYPHIMURIUM BY ETHIONINE.
作者信息
SMITH R C, SALMON W D
出版信息
J Bacteriol. 1965 Jun;89(6):1494-8. doi: 10.1128/jb.89.6.1494-1498.1965.
Smith, Robert C. (Auburn University, Auburn. Ala.), and W. D. Salmon. Enhancement by adenine of the inhibition of Salmonella typhimurium by ethionine. J. Bacteriol. 89:1494-1498. 1965.-The inhibition by ethionine of the growth of Salmonella typhimurium was increased by adenine and several other purines. This effect was counteracted by the addition of methionine to the cultures. There was no preferential inhibition of nucleic acid or protein synthesis by adenine plus ethionine. Adenine stimulated the uptake of radioactive ethionine by the cells. Adenine may produce the effects observed by increasing the rate at which ethionine enters the cell and reaches its primary site of antibacterial action.
史密斯，罗伯特·C.（奥本大学，奥本，阿拉巴马州）和W.D.萨蒙。腺嘌呤增强乙硫氨酸对鼠伤寒沙门氏菌的抑制作用。《细菌学杂志》89:1494 - 1498。1965年。——腺嘌呤和其他几种嘌呤增强了乙硫氨酸对鼠伤寒沙门氏菌生长的抑制作用。向培养物中添加蛋氨酸可抵消这种作用。腺嘌呤加乙硫氨酸对核酸或蛋白质合成没有优先抑制作用。腺嘌呤刺激细胞对放射性乙硫氨酸的摄取。腺嘌呤可能通过提高乙硫氨酸进入细胞并到达其主要抗菌作用位点的速率而产生所观察到的效果。
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