Bernard J F
Nouv Rev Fr Hematol Blood Cells. 1977;18(1):117-37.
In this paper we review our knowledge on: 1. The physiological mechanisms of constant low Na+, high K+ concentration in human red blood cells (cation content, cation movements through the erythrocyte membrane, membrane ATPases). 2. The pathologic findings observed in congenital hemolytic anemia. These alterations may explain hyperhemolysis in numerous diseases. In no case a primary genetically transmitted abnormal erythrocyte membrane protein can be formely demonstrated.
在本文中,我们综述了以下方面的知识:1. 人类红细胞中持续低钠高钾浓度的生理机制(阳离子含量、阳离子通过红细胞膜的运动、膜ATP酶)。2. 先天性溶血性贫血中观察到的病理发现。这些改变可能解释了许多疾病中的高溶血现象。在任何情况下,以前都无法证明存在原发性遗传传递的异常红细胞膜蛋白。