Reisert I, Steinhardt B, Flach A, Tonutti E
Monatsschr Kinderheilkd (1902). 1977 Feb;125(2):82-7.
The following conclusions which show the importance of time of medical treatment resulted from the examination of 288 testicular biopsies (including 46 controls) by statistical analysis in correlation to age. 1. There is no difference in the number of spermatogonia per tubule cross section of descended and undescended testes in children from birth to 2 years of age. 2. The number of spermtogonia in descended testes is not different in children from birth to 2 years in comparison to children aged 2-6 years. 3. A statistically significant decrease of spermatogonia takes place in the undescended testes of children from 2-6 years in comparison to children from birth to 2 years. 4. The difference in the number of spermatogonia of descended and undescended testes increases in children above the age of 2. It must be concluded from this study that the pathological alterations of the germinative epithelium increase in children beyond the age of 2. Assuming that pathological alterations of the germinative epithelium are caused by the dystopy of the testes, medical treatment should be carried out before the child is more than 2 years old.
通过对288例睾丸活检(包括46例对照)与年龄进行相关性统计分析,得出以下显示治疗时间重要性的结论。1. 出生至2岁儿童的降睾和隐睾每小管横截面积精原细胞数量无差异。2. 出生至2岁儿童的降睾精原细胞数量与2 - 6岁儿童相比无差异。3. 与出生至2岁儿童相比,2 - 6岁儿童隐睾中的精原细胞有统计学意义的减少。4. 2岁以上儿童降睾和隐睾的精原细胞数量差异增大。从这项研究可以得出结论,2岁以上儿童生精上皮的病理改变会增加。假设生精上皮的病理改变是由睾丸异位引起的,医疗治疗应在儿童2岁之前进行。