Levêque J, Giono A, Poulain P, Broux P L, Loget P, Kerbrat P, Kérisit J, Grall J Y, Giraud J R
Service Gynécologie-Obstétrique B, Hôpital Sud, Rennes.
J Gynecol Obstet Biol Reprod (Paris). 1992;21(6):616-24.
The authors report nine personal cases in a review of the literature concerning cancers of the breast associated with pregnancy and lactation (until a year post-partum). The diagnosis of the illness is reported to be difficult in pregnant women and it is necessary to use fully all the diagnostic procedures available and in particular cytology and histology. Surgery is urgent. It is classical practice to carry out a mastectomy with axillary clearance. Nevertheless more conservative treatments are now being suggested. The principal problem of therapy is linked to the effects of adjuvant therapy on the fetus be they radiotherapy or chemotherapy, particularly because it is very important that treatments should be thorough and start early in the pregnancy. The overall prognosis is bad because pregnancy seems above all to aggravate serious forms of the disease.
作者在一篇关于妊娠和哺乳期(直至产后一年)相关乳腺癌的文献综述中报告了9例个人病例。据报道,孕妇的疾病诊断困难,有必要充分利用所有可用的诊断程序,尤其是细胞学和组织学检查。手术刻不容缓。经典做法是进行乳房切除术并清扫腋窝。然而,现在有人提出更保守的治疗方法。治疗的主要问题与辅助治疗对胎儿的影响有关,无论是放疗还是化疗,特别是因为治疗必须彻底且在妊娠早期开始非常重要。总体预后不佳,因为妊娠似乎首先会加重严重的疾病形式。