Bhattacharya S K, Bhattacharya M K, Ramamurthy T, Pal A, Bag P K, Takeda T, Shimada T, Dutta P, Debnath A, Chakraborti S
National Institute of Cholera and Enteric Diseases, Beliaghata, Calcutta, India.
J Diarrhoeal Dis Res. 1992 Sep;10(3):161-3.
An Australian tourist suffering from severe acute watery diarrhoea and dehydration due to Vibrio cholerae non-01 was studied. The V. cholerae strain isolated from the patient belonged to serovar 05. The organism did not produce any of the conventional enterotoxins including cholera-toxin (CT) or heat-stable toxins (NAG-ST) that are known to be associated with intestinal secretion. This report suggests that toxin(s) other than CT-like or NAG-ST may be involved in the pathogenesis of diarrhoea by some V. cholerae non-01 strains.
对一名因非01群霍乱弧菌感染而患有严重急性水样腹泻和脱水的澳大利亚游客进行了研究。从该患者分离出的霍乱弧菌菌株属于05血清型。该菌株不产生任何已知与肠道分泌相关的传统肠毒素,包括霍乱毒素(CT)或热稳定毒素(NAG-ST)。本报告表明,除CT样毒素或NAG-ST之外的毒素可能参与了某些非01群霍乱弧菌菌株引起腹泻的发病机制。