Palestro C J, Schultz B, Horowitz M, Swyer A J
Long Island Jewish Medical Center, New York, New York.
J Nucl Med. 1992 Nov;33(11):2027-9.
Two young women with acute sarcoidosis underwent (111)In-labeled autologous leukocyte imaging because of persistent fevers. Images of one of the women demonstrated faint thoracic lymph node uptake of labeled cells, but no discrete focus suggestive of infection was seen. Images of the second woman were normal. Gallium-67 imaging, performed 48 hr after the leukocyte studies, revealed multiple areas of abnormal radiotracer accumulation corresponding to regions of active sarcoid in both women. These cases suggest that leukocyte imaging is not useful for assessing the extent of disease in patients with sarcoidosis. This technique may be valuable, however, in excluding superimposed infection in these individuals.
两名患有急性结节病的年轻女性因持续发热接受了铟-111标记的自体白细胞显像。其中一名女性的图像显示标记细胞在胸部淋巴结有微弱摄取,但未见提示感染的离散病灶。第二名女性的图像正常。在白细胞研究后48小时进行的镓-67显像显示,两名女性均有多个与活跃结节病区域相对应的放射性示踪剂异常聚集区域。这些病例表明,白细胞显像对评估结节病患者的疾病范围无用。然而,这项技术在排除这些个体的叠加感染方面可能有价值。