Bennett C P, Davis T, Seller M J
Division of Medical and Molecular Genetics, Guy's Hospital, London.
J Med Genet. 1992 Oct;29(10):745-6. doi: 10.1136/jmg.29.10.745.
Prenatal diagnosis of an IVF pregnancy in a woman aged 41 years showed a fetus mosaic for trisomy 15. The fetus had dysmorphic features, hypoplastic adrenal glands, and an accessory spleen. Both IVF and advanced maternal age would seem to increase the risk of trisomy 15.
对一名41岁女性体外受精(IVF)妊娠进行的产前诊断显示,胎儿为15三体嵌合体。该胎儿具有畸形特征、肾上腺发育不全和副脾。体外受精和高龄似乎都会增加15三体的风险。