Tsuji S, Anglade P, Ozaki T, Sazi T, Yokoyama S
Départment de Cytologie, Université Pierre et Marie Curie, Paris, France.
Jpn J Physiol. 1992;42(3):363-75. doi: 10.2170/jjphysiol.42.363.
Computerized analysis of video-recorded peristalsis was made in a preparation of guinea-pig ileum tube from which both mucosa and submucosa were mechanically scraped off. Threshold value for provoking peristalsis was higher, conduction velocity of peristalsis was slower, and peristaltic force was weaker in comparison with the ileum tube from which only mucosa was scraped off and with the normal ileum tube. A histological control of the preparation proved that there was no nerve cell body of submucous plexus on the surface of separated circular muscle. It was concluded that peristalsis, though impaired, could be provoked by way of activation of the reflex arch consisted by neural circuit of myenteric neurons which should be produced by excitation of stretch receptors in the muscularis externa.
对豚鼠回肠管进行录像，然后对其蠕动进行计算机分析，该回肠管的黏膜和黏膜下层均被机械刮除。与仅刮除黏膜的回肠管和正常回肠管相比，引发蠕动的阈值更高，蠕动传导速度更慢，且蠕动力量更弱。对该标本的组织学对照证明，分离出的环行肌表面没有黏膜下神经丛的神经细胞体。得出的结论是，虽然蠕动受损，但可通过激活由肌间神经元神经回路组成的反射弧来引发蠕动，该反射弧应由外肌层牵张感受器的兴奋产生。
