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[Antibody detection in zoonotic cutaneous leishmaniasis by using the indirect immunofluorescence reaction and C-ELISA in different clinical manifestations of the disease].

作者信息

Khuseĭinova Kh Kh, Dobrzhanskaia R S, Saf'ianova V M, Gracheva L I, Goncharov D B, Khanafieva I V

出版信息

Med Parazitol (Mosk). 1992 May-Jun(3):11-3.

PMID:1435548
Abstract

189 sera from patients with ZCL of different stages were studied by means of RNIF and C-ELISA. A high significant correlation between RNIF and C-ELISA indices was shown, but the latter test was proved to be more sensitive and therefore more effective. In patients with ZCL, a significant direct correlation between the duration of the process and the antibody titer was established by means of C-ELISA. In patients with ZCL at the third (final) stage (reduction and granulation of lesions), the C-ELISA liter of specific antibodies was higher than at the second stage (rapidly progressing ulceration of lesions). The findings indicate the presence of clinical and serological parallels in ZCL and show it expedient to compare the dynamics of antibody genesis and cell immunity indices in further studies.

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