一种影响结核性豚鼠琥珀酸脱氢酶活性的组织因子。

A tissue factor influencing succinic dehydrogenase activity in tuberculous guinea pigs.

作者信息

MARTIN S P, COOPER C D, CHAUDHURI S N, GREEN R

出版信息

J Exp Med. 1955 Jun 1;101(6):639-46. doi: 10.1084/jem.101.6.639.

DOI:10.1084/jem.101.6.639

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2136487/

Abstract

The alterations in succinic dehydrogenase activity during the course of infection with Mycobacterium tuberculosis strains H37Rv and BCG, as well as with dead bacilli, has been described. A tissue factor has been described which is prepared from normal bovine kidney and will restore enzyme activity in vitro. This factor is prepared by chromatographic analysis and contains a nucleotide with an ultraviolet absorption maxima at 250 mmicro (pH 3) and a free sulfhydryl group. The role of this factor in the response to tuberculosis is discussed.

摘要

已经描述了在感染结核分枝杆菌H37Rv株和卡介苗以及死菌过程中琥珀酸脱氢酶活性的变化。已经描述了一种从正常牛肾制备的组织因子，它能在体外恢复酶活性。该因子通过色谱分析制备，含有一种在250微米（pH 3）处有最大紫外吸收的核苷酸和一个游离巯基。讨论了该因子在结核病反应中的作用。

相似文献

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A tissue factor influencing succinic dehydrogenase activity in tuberculous guinea pigs.一种影响结核性豚鼠琥珀酸脱氢酶活性的组织因子。

J Exp Med. 1955 Jun 1;101(6):639-46. doi: 10.1084/jem.101.6.639.

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引用本文的文献

1

Metabolism in infection: study on the enzymatic damage in kidney of guinea pig infected with Mycobacterium tuberculosis.感染中的代谢：对感染结核分枝杆菌的豚鼠肾脏酶损伤的研究。

J Exp Med. 1963 Jan 1;117(1):71-9. doi: 10.1084/jem.117.1.71.

2

Determination of dehydrogenases in atypical strains and in other Mycobacteria.非典型菌株及其他分枝杆菌中脱氢酶的测定

J Bacteriol. 1959 Jun;77(6):748-52. doi: 10.1128/jb.77.6.748-752.1959.

3

[Mechanisms of nonspecific infection resistance].[非特异性抗感染机制]

Klin Wochenschr. 1958 Sep 15;36(18):837-45. doi: 10.1007/BF01485228.

本文引用的文献

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FACTORS AFFECTING THE GROWTH OF TUBERCLE BACILLI IN LIQUID MEDIA.影响液体培养基中结核分枝杆菌生长的因素。

J Exp Med. 1946 Apr 30;83(5):409-23.

2

A respiratory catalyst required for the reduction of cytochrome c by cytochrome b.一种细胞色素b还原细胞色素c所需的呼吸催化剂。

Biochem J. 1949;45(1):14-30. doi: 10.1042/bj0450014.

3

An improved method for the colorimetric determination of phosphate.一种改进的比色法测定磷酸盐的方法。

Biochem J. 1938 Feb;32(2):295-8. doi: 10.1042/bj0320295.

4

Some reactions of adenosine and inosine phosphates in animal tissues.动物组织中腺苷酸和肌苷酸的一些反应。

Biochim Biophys Acta. 1953 Sep-Oct;12(1-2):172-80. doi: 10.1016/0006-3002(53)90136-x.

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