克赖斯特彻奇社区的病毒性肝炎
Viral hepatitis in the Christchurch community.
作者信息
Chapman B A, Hann D J, Schousboe M I, Burt M J, Wilkinson I D, George P M
机构信息
Department of Gastroenterology, Christchurch Hospital.
出版信息
N Z Med J. 1992 Sep 23;105(942):376-7.
AIM
To determine the relative frequency of known causes of viral hepatitis in the Christchurch community.
METHODS
Serum samples were collected at a private laboratory from patients aged 15-75 years who had an elevated transaminase of at least twice normal.
RESULTS
One hundred and thirty-three subjects entered the study of whom 32 were positive for Epstein Barr virus, three for cytomegalovirus, nine for hepatitis A virus, and eight for hepatitis B virus. Paired convalescent samples were obtained from 64 of the remaining 81 subjects (17 lost or declined) and seven of these were positive for hepatitis C. Assuming a similar percentage in the lost/declined group this corrects to nine.
CONCLUSION
The relative frequency of viral agents causing hepatitis was Epstein Barr virus 52%, cytomegalovirus 5%, hepatitis A virus 15%, hepatitis B virus 13% and hepatitis C virus 15%. Hepatitis C virus is a common cause of viral hepatitis in the Christchurch community.
目的
确定克赖斯特彻奇社区已知病毒性肝炎病因的相对频率。
方法
在一家私人实验室收集了年龄在15至75岁之间、转氨酶至少升高至正常水平两倍的患者的血清样本。
结果
133名受试者进入研究，其中32人 Epstein Barr病毒检测呈阳性，3人巨细胞病毒检测呈阳性，9人甲型肝炎病毒检测呈阳性，8人乙型肝炎病毒检测呈阳性。从其余81名受试者中的64人（17人失访或拒绝）获取了配对的恢复期样本，其中7人丙型肝炎病毒检测呈阳性。假设失访/拒绝组中的比例相似，校正后为9人。
结论
引起肝炎的病毒病原体相对频率为：Epstein Barr病毒52%，巨细胞病毒5%，甲型肝炎病毒15%，乙型肝炎病毒13%，丙型肝炎病毒15%。丙型肝炎病毒是克赖斯特彻奇社区病毒性肝炎的常见病因。
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