Bretland P M
Chinese University of Hong Kong, Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Sha Tin.
Nucl Med Commun. 1992 Feb;13(2):106-9.
Diuresis renography should exclude or confirm pelvi-ureteric junction obstruction. Numerous equivocal cases seen here had large renal pelves with slow emptying on frusemide diuresis. An attempt was made to relate the rate of emptying to the volume of the renal pelvis. The fully distended renal pelvis during frusemide diuresis appears to satisfy the criteria of the single compartmental model which predicts a linear relationship between volume and flow rate, i.e. F = [0.693 V0]/t1/2 where F is the flow rate, V0 is the volume and t1/2 the time at which half the tracer has disappeared. Clearance half-time was measured from the diuresis renogram curve. Volume was estimated from a longitudinal ultrasound image at the end of the procedure, using a volumetric version of Simpson's rule as a sequential slice technique, given a roughly circular transverse image. Of 18 kidneys in 14 adult patients, three had large volume pelves and short emptying times. The remaining 15 showed a roughly linear relationship between volume as estimated and clearance half-time. This appears to validate both the theory and the method and permits calculation of the pelvic outflow rate. An hypothesis to explain the large unobstructed renal pelvis is advanced.
利尿肾图应排除或证实肾盂输尿管连接处梗阻。在此处观察到的众多模棱两可的病例中，许多肾盂较大，在使用速尿进行利尿时排空缓慢。我们尝试将排空速率与肾盂体积联系起来。速尿利尿期间完全扩张的肾盂似乎符合单室模型的标准，该模型预测体积与流速之间呈线性关系，即F = [0.693 V0]/t1/2，其中F是流速，V0是体积，t1/2是示踪剂消失一半时的时间。清除半衰期是从利尿肾图曲线测量的。在操作结束时，使用辛普森法则的体积版本作为序列切片技术，根据大致圆形的横向图像，从纵向超声图像估计体积。在14名成年患者的18个肾脏中，3个肾盂体积大且排空时间短。其余15个肾脏显示估计体积与清除半衰期之间大致呈线性关系。这似乎验证了理论和方法，并允许计算肾盂流出率。我们提出了一个假说来解释肾盂大但无梗阻的情况。
