[Modern problems of drug allergy to antibiotics in the clinical aspects of skin and venereal diseases].

Allergic dermatoses induced by antibiotics amounted to 45.2 per cent of all determined drug reactions according to the data of the Kharkov Research Institute of Dermatology and Venerology. The data on the factors favouring development of the drug dermatoses are presented. Difficulties in differential diagnosis by means of clinical and laboratory methods are indicated. The modern immunological tests of etiological diagnosis of drug resistance and the results of studying non-specific reactivity in patients with medicamentous dermatoses were analyzed. The principles of therapy and prophylaxis are summarized.