Tomaselli C E
Spec Care Dentist. 1992 May-Jun;12(3):107-11. doi: 10.1111/j.1754-4505.1992.tb00424.x.
The geriatric population constitutes the largest group of consumers of medications in this country. Changes in the pharmacokinetic response to medications of this population are less predictable than in younger age groups, thereby resulting in adverse reactions and drug interactions in multidrug users. Dentists need to be aware of these changes as well as alterations in therapeutic responses to the medications most commonly used in dental treatment: sedatives, local anesthetics, analgesics, and antibiotics.
老年人群体是该国最大的药物消费群体。与年轻人群体相比，该群体对药物的药代动力学反应变化更难预测，从而导致多药使用者出现不良反应和药物相互作用。牙医需要了解这些变化以及牙科治疗中最常用药物（镇静剂、局部麻醉剂、镇痛药和抗生素）的治疗反应变化。
