Krippaehne J A, Montgomery M T
University of Texas Health Science Center, San Antonio.
Spec Care Dentist. 1992 May-Jun;12(3):125-30. doi: 10.1111/j.1754-4505.1992.tb00428.x.
Erythema multiforme is a florid mucocutaneous disease characterized by oral, cutaneous, and ocular manifestations. The cutaneous lesions are pathognomonic because of their unique "target-like" appearance. A severe form of EM has been termed "Stevens-Johnson Syndrome". Although the etiology of EM is unknown, much of the research suggests an immunological association with HSV. The diagnosis of EM is based on signs and symptoms, and a differential diagnosis should include other ulcerative, mucocutaneous diseases, such as erosive lichen planus, pemphigus, varicella zoster, ANUG, TEN, aphthous stomatitis, and primary HSV. Therapeutic measures are palliative, including a soft bland diet, topical anesthetics, and corticosteroids. A case of EM is described which underscores the appearance of the disease and its clinical course.
多形红斑是一种以口腔、皮肤和眼部表现为特征的急性黏膜皮肤疾病。皮肤损害因其独特的“靶样”外观而具有诊断意义。严重的多形红斑被称为“史蒂文斯-约翰逊综合征”。虽然多形红斑的病因尚不清楚，但许多研究表明其与单纯疱疹病毒存在免疫关联。多形红斑的诊断基于体征和症状，鉴别诊断应包括其他溃疡性黏膜皮肤疾病，如糜烂性扁平苔藓、天疱疮、水痘带状疱疹、急性坏死性溃疡性龈炎、中毒性表皮坏死松解症、复发性阿弗他口炎和原发性单纯疱疹病毒感染。治疗措施为姑息性的，包括软质清淡饮食、局部麻醉剂和皮质类固醇。本文描述了一例多形红斑病例，强调了该病的外观及其临床病程。
