Faine M P, Allender D, Baab D, Persson R, Lamont R J
University of Washington, School of Dentistry, Seattle.
Spec Care Dentist. 1992 Jul-Aug;12(4):177-82. doi: 10.1111/j.1754-4505.1992.tb00441.x.
In this pilot study, dietary habits, microbial factors, and salivary factors in 20 older adults who had active decay on root surfaces were compared with those of 20 adults who had inactive or no root caries. In this case-control study, the groups were matched by sex and were of similar age. Subjects using medications known to induce dry mouth were excluded. Subjects completed a nutrition interview and a four-day food diary. Stimulated whole saliva flow rate, buffering capacity, levels of salivary lactobacilli with use of the Dentocult method, and S. mutans cultured on MSB agar were determined. The root caries group had a greater mean number of eating occasions per day (6.1 vs. 4.6), more frequent exposures to fermentable carbohydrates (5.8 vs. 4.2), and higher average daily sugars intake (133 g/day vs. 105 g/day) than the control group. Root caries subjects had significantly higher lactobacilli counts and less salivary buffering capacity. Within the root caries group, significant correlations were found with Root Caries Index and lactobacilli (r = 0.56) and S. mutans counts (rs = 0.50). These results show that frequent intake of simple sugars, high lactobacilli counts, and low saliva buffering capacity may be risk factors associated with root caries in older adults.
在这项试点研究中，将20名有根面活动性龋坏的老年人的饮食习惯、微生物因素和唾液因素，与20名无活动性根龋或无根龋的成年人进行了比较。在这项病例对照研究中，两组按性别匹配且年龄相近。排除使用已知会导致口干药物的受试者。受试者完成了营养访谈和为期四天的食物日记。测定了刺激全唾液流速、缓冲能力、使用Dentocult方法检测的唾液乳酸杆菌水平以及在MSB琼脂上培养的变形链球菌。根龋组每天的进食次数平均数更多（6.1次对4.6次），接触可发酵碳水化合物的频率更高（5.8次对4.2次），每日平均糖摄入量也更高（133克/天对105克/天）。根龋受试者的乳酸杆菌计数显著更高，唾液缓冲能力更低。在根龋组中，发现根龋指数与乳酸杆菌（r = 0.56）和变形链球菌计数（rs = 0.50）之间存在显著相关性。这些结果表明，频繁摄入单糖、高乳酸杆菌计数和低唾液缓冲能力可能是与老年人根龋相关的危险因素。
